I'll be honest...
The animation and artwork are very lackluster, however, assuming it's your first cartoon, it's surprisingly better than most peoples' first attempts at Flash. My suggestions would be to avoid choosing ambitious projects for your first submission, because you'll only end up getting frustrated and wasting a possible well written story on a piece of work with terrible graphics and animation.
With your level of skill, I'd recommend doing several small projects first, before trying to make something like this. I can tell you have intentions of creating something decent for Newgrounds, but as of now, your abilities with drawings and animation need to be practiced. Keep trying--I actually gave up with Flash several times before I finally settled down and made good material.